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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BRF1 All Species: 4.55
Human Site: S436 Identified Species: 7.69
UniProt: Q92994 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q92994 NP_001510.2 677 73840 S436 E C I S S Q S S D P K D A S G
Chimpanzee Pan troglodytes XP_510208 819 88957 S578 E C I S S Q S S D P K D A S G
Rhesus Macaque Macaca mulatta XP_001098066 599 65136 L371 S G D G E L D L S G I D D L E
Dog Lupus familis XP_548005 637 70371 D409 P C G D G E L D L S G I D D L
Cat Felis silvestris
Mouse Mus musculus Q8CFK2 676 73781 G435 E C I S S P S G D P K D S S G
Rat Rattus norvegicus NP_001100231 686 74096 G445 E C I S S P S G D P K D S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_421405 681 75256 R441 E C I S S K D R E P G E N T G
Frog Xenopus laevis NP_001088063 660 73751 Q428 E C I A M H E Q E K S D N A G
Zebra Danio Brachydanio rerio NP_956183 693 76806 I435 S L G L T D S I R Q C I T E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650616 662 73627 L434 K Q P Q E Q E L I T D D L N D
Honey Bee Apis mellifera XP_623775 648 73504 N420 V N I N F E N N S G E I D V A
Nematode Worm Caenorhab. elegans NP_495526 759 84015 E434 I V N A D L E E D I S D S E I
Sea Urchin Strong. purpuratus XP_794011 768 83924 E503 I K E A A I P E E K S P D S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29056 596 66888 H368 I D G E N I Y H E G S E N E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 79.3 86.4 82.7 N.A. 89.8 81.6 N.A. N.A. 78.1 72.5 65.9 N.A. 42.5 43.4 32.4 46.3
Protein Similarity: 100 80 87 85.9 N.A. 93.3 86 N.A. N.A. 87 84.7 77.6 N.A. 59.6 61.7 50 60.1
P-Site Identity: 100 100 6.6 6.6 N.A. 80 80 N.A. N.A. 46.6 33.3 6.6 N.A. 13.3 6.6 13.3 6.6
P-Site Similarity: 100 100 6.6 13.3 N.A. 86.6 86.6 N.A. N.A. 73.3 53.3 13.3 N.A. 26.6 40 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 27.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 22 8 0 0 0 0 0 0 0 15 8 8 % A
% Cys: 0 50 0 0 0 0 0 0 0 0 8 0 0 0 0 % C
% Asp: 0 8 8 8 8 8 15 8 36 0 8 58 29 8 15 % D
% Glu: 43 0 8 8 15 15 22 15 29 0 8 15 0 22 8 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 22 8 8 0 0 15 0 22 15 0 0 0 43 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % H
% Ile: 22 0 50 0 0 15 0 8 8 8 8 22 0 0 8 % I
% Lys: 8 8 0 0 0 8 0 0 0 15 29 0 0 0 0 % K
% Leu: 0 8 0 8 0 15 8 15 8 0 0 0 8 8 8 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 8 8 8 0 8 8 0 0 0 0 22 8 0 % N
% Pro: 8 0 8 0 0 15 8 0 0 36 0 8 0 0 0 % P
% Gln: 0 8 0 8 0 22 0 8 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 8 0 0 0 0 0 0 % R
% Ser: 15 0 0 36 36 0 36 15 15 8 29 0 22 36 0 % S
% Thr: 0 0 0 0 8 0 0 0 0 8 0 0 8 8 15 % T
% Val: 8 8 0 0 0 0 0 0 0 0 0 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _